Details of the Drug

General Information of Drug (ID: DMMF6UB)

Drug Name

GE-1170A

Synonyms

Elongation factor Tu inhibitors (bacterial infection); LDI-028; LDK-733; Elongation factor Tu inhibitors (bacterial infection), Novartis

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Phase 1	[1]
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Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Staphylococcus Elongation factor Tu (Stap-coc tuf)	TTYQIFM	EFTU_STAAS	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	GE2270A-resistant mutations in elongation factor Tu allow productive aminoacyl-tRNA binding to EF-Tu.GTP.GE2270A complexes. J Mol Biol. 2000 Dec 15;304(5):995-1005.