Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMXZBK)

Drug Name

NSC-39851 Drug Info

Synonyms

Aminomethanesulfonic acid; Aminomethanesulfonic acid, 97%; Aminomethanesulphonic acid; Methanesulfonic acid, 1-amino-; Methanesulfonic acid, amino-; OBESRABRARNZJB-UHFFFAOYSA-N; OLA224Z482; Sodium aminomethanesulphonate; amino-methanesulfonicaci; aminomethanesulfonic; aminomethanesulfonicacid; aminomethanesulfoniccid; aminomethylsulfonic acid; (Aminomethyl)sulfonic acid; 13881-91-9; 6939-85-1; 87993-99-5; EINECS 230-076-2; EINECS 237-649-6; MFCD00008124; NSC 209983; NSC 39851; NSC39851; UNII-OLA224Z482

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 83791
CAS Number: CAS 13881-91-9
TTD Drug ID: DMMXZBK
INTEDE Drug ID: DR2024

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Metabolized By Bile acid-CoA thioesterase (BAAT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Glycine	DMIOZ29	Malnutrition	5B50-5B71	Approved	[2]
Obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[3]
Taurine	DMVW7N3	Discovery agent	N.A.	Investigative	[2]
ZX-AP000068	DM4Y0NI	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Bile acid-CoA thioesterase (BAAT)^{Main DME}	DERA3OF	BAAT_HUMAN	Substrate	[2]

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References

1	PubChem 2019 update: improved access to chemical data. Nucleic Acids Res. 2019 Jan 8; 47(D1):D1102-1109. (PubChem CID: 83791)
2	Bile acid coenzyme A: amino acid N-acyltransferase in the amino acid conjugation of bile acids. Methods Enzymol. 2005;400:374-94.
3	Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. J Biol Chem. 1994 Jul 29;269(30):19375-9.