Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMN72OM)

Drug Name

U300 Drug Info

Synonyms

Methyl 3,5-dinitrobenzoate; 2702-58-1; Benzoic acid, 3,5-dinitro-, methyl ester; POGCCFLNFPIIGW-UHFFFAOYSA-N; 3,5-dinitro-benzoic acid methyl ester; Methyl 3,5-Dinitrobenzoate,99%; Methyl-3,5-dinitrobenzoate; U300; ACMC-1CR6Q; AC1L5B8W; AC1Q5AI0; KSC494Q3H; SCHEMBL418416; Jsp005266; CHEMBL2252127; CTK3J4833; KS-00000ZZJ; NSC7317; MolPort-001-012-121; Methyl 3,5-dinitrobenzoate, 99%; ALBB-024845; NSC-7317; ZINC1683476; METHYL-3,5-DINITRO BENZOATE; BBL000013; ANW-44565; SBB068882; MFCD00017016; STK386186; 3,5-Dinitrobenzoic acid methyl e

Indication

Disease Entry	ICD 11	Status	REF
Type-2 diabetes	5A11	Phase 3	[1]

Cross-matching ID

PubChem CID: 222067
CAS Number: CAS 2702-58-1
TTD Drug ID: DMN72OM

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

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Drug(s) Targeting Insulin (INS)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Inulin	DM1Y2JH	Measure kidney function	MG02	Approved	[3]
Insulin Zinc Susp Recombinant Human	DM6MO9X	Diabetic complication	5A2Y	Approved	[3]
Insulin-glargine	DMR4HIW	Diabetic complication	5A2Y	Approved	[3]
Insulin Susp Isophane Recombinant Human	DMW8KI7	Diabetic complication	5A2Y	Approved	[3]
Insulin determir	DM79NZ5	Diabetic complication	5A2Y	Approved	[4]
Insulin Susp Protamine Zinc Beef/Pork	DM0NATE	Diabetic complication	5A2Y	Approved	[3]
Insulin-aspart	DMX7V28	Diabetic complication	5A2Y	Approved	[3]
Insulin degludec	DMPL395	Type-1/2 diabetes	5A10-5A11	Approved	[5]
Insulin-detemir	DMOA4VW	Type-1/2 diabetes	5A10-5A11	Approved	[3]
LY2963016	DMEZ0H5	Type-1/2 diabetes	5A10-5A11	Phase 3	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Insulin (INS)	TTZOPHG	INS_HUMAN	Modulator	[2]

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References

1	Clinical pipeline report, company report or official report of Sanofi.
2	U300, a novel long-acting insulin formulation. Expert Opin Biol Ther. 2014 Dec;14(12):1849-60.
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
4	2005 approvals: Safety first. Nature Reviews Drug Discovery 5, 92-93 (February 2006).
5	Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651.
6	Efficacy and safety of LY2963016 insulin glargine compared with insulin glargine (Lantus ) in patients with type 1 diabetes in a randomized controlled trial: the ELEMENT 1 study. Diabetes Obes Metab.2015 Aug;17(8):726-33.