General Information of Drug (ID: DMOBEL9)

Drug Name
7,8,3',4'-tetrahydroxyflavone Drug Info
Synonyms
7,8,3',4'-tetrahydroxyflavone; 3440-24-2; 2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4H-chromen-4-one; 3',4',7,8-Tetrahydroxyflavone; CHEMBL222541; ARYCMKPCDNHQCL-UHFFFAOYSA-N; ST059620; 2-(3,4-dihydroxyphenyl)-7,8-dihydroxychromen-4-one; AC1LEMTC; AC1Q6AJ1; SCHEMBL35318; CTK4H2335; ZINC57844; DTXSID20350973; 2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4h-chromen-4-on; CHEBI:125596; 7,8,3'',4''-tetrahydroxyflavone; BDBM50157547; AKOS024283046; ACM3440242; MCULE-5496936655; ZB002260; DB-048618; FT-0614178; C-57754
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
688798
ChEBI ID
CHEBI:125596
CAS Number
CAS 3440-24-2
TTD Drug ID
DMOBEL9

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [2]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [2]
2,7-Bis(acetamido)anthraquinone DM2EPM4 Discovery agent N.A. Investigative [3]
2,7-Bis(cyclohexanecarbonamido)anthraquinone DMTPZ8D Discovery agent N.A. Investigative [3]
2,7-Bis[2-(isopropylamino)acetamido]anthraquinone DMRQGWX Discovery agent N.A. Investigative [3]
NSC-745884 DM8W0J3 Discovery agent N.A. Investigative [4]
2,7-Bis[3-(piperidino)propionamido]anthraquinone DMET693 Discovery agent N.A. Investigative [3]
2,7-Bis(cyclopropanecarbonamido)anthraquinone DMY3V2B Discovery agent N.A. Investigative [3]
2,7-Bis(phenylacetamido)anthraquinone DMEVIBT Discovery agent N.A. Investigative [3]
NSC-745887 DMG9BWY Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TERT messenger RNA (TERT mRNA) TTQY2EJ TERT_HUMAN Inhibitor [1]

References

1 Catecholic flavonoids acting as telomerase inhibitors. J Med Chem. 2004 Dec 16;47(26):6466-75.
2 Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.
3 Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86.
4 Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28.