Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOTJWZ)

Drug Name

1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone Drug Info

Synonyms

1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone; CHEMBL493448; SCHEMBL10247513; CHEMBL1187207; BDBM50252801; DB07342; 1(adamantan1yl) 2(1himidazol1yl) ethanone; 1-(adamantan-1-yl)-2-(imidazol-1-yl)ethanone; 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone hydrochloride

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 20541332
TTD Drug ID: DMOTJWZ

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Heme oxygenase 1 (HMOX1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Stannsoporfin	DMEG4TC	Neonatal hyperbilirubinemia	KA87	Phase 2	[2]
Heme	DMGC287	Discovery agent	N.A.	Investigative	[1]
Formic Acid	DMNFZC6	Discovery agent	N.A.	Investigative	[3]
2-Propanol, Isopropanol	DML5O0H	Discovery agent	N.A.	Investigative	[3]
2-Phenylheme	DMPIQTE	Discovery agent	N.A.	Investigative	[3]
Biliverdine Ix Alpha	DMCA0WJ	N. A.	N. A.	Investigative	[3]
Verdoheme	DM7NRK5	Discovery agent	N.A.	Investigative	[4]
Tin protoporphyrin	DMTXJ5S	Discovery agent	N.A.	Investigative	[5]
12-Phenylheme	DMLR2FB	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Heme oxygenase 1 (HMOX1)	TTI6V2A	HMOX1_HUMAN	Inhibitor	[1]

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References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2	Chemoprevention of severe neonatal hyperbilirubinemia. Semin Perinatol. 2004 Oct;28(5):365-8.
3	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4	DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.
5	Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation. Circulation. 2001 Nov 27;104(22):2710-5.