General Information of Drug (ID: DMOX8JF)

Drug Name
ISIS 107652 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DMOX8JF

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isoquinoline-1,3,4(2H)-trione DMT4RI2 Discovery agent N.A. Investigative [2]
Acetyl-Ile-Glu-Thr-Asp-aldehyde DM1VE6S Discovery agent N.A. Investigative [3]
ISIS 107612 DMBWCZR Discovery agent N.A. Investigative [1]
ISIS 107676 DMUE64H Discovery agent N.A. Investigative [1]
ISIS 107681 DMB9VFS Discovery agent N.A. Investigative [1]
ISIS 107642 DMPR7OD Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Caspase 8 messenger RNA (CASP8 mRNA) TT6SZNG CASP8_HUMAN Not Available [1]

References

1 US patent application no. 6,258,600, Antisense modulation of caspase 8 expression.
2 Design, synthesis, and biological evaluation of isoquinoline-1,3,4-trione derivatives as potent caspase-3 inhibitors. J Med Chem. 2006 Mar 9;49(5):1613-23.
3 Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6. J Med Chem. 2009 Apr 23;52(8):2188-91.