General Information of Drug (ID: DMBWCZR)

Drug Name
ISIS 107612
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Antisense drug
Sequence
CTGCTCAGACAGCAGATGCT
Cross-matching ID
TTD ID
D00JXJ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Caspase 8 messenger RNA (CASP8 mRNA) TT6SZNG CASP8_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Caspase 8 messenger RNA (CASP8 mRNA) DTT CASP8 8.78E-06 1.43 4.51
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 US patent application no. 6,258,600, Antisense modulation of caspase 8 expression.