Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMP3RCH)

Drug Name
US8846654, 294 Drug Info
Synonyms BDBM135584; US8846654, 294
Cross-matching ID
PubChem CID
72333047
TTD Drug ID
DMP3RCH

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Phosphodiesterase 8 (PDE8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
US8846654, 251 DMML258 N. A. N. A. Patented [1]
US8846654, 11 DMRUTJZ N. A. N. A. Patented [1]
US9493447, 1001 DM4MJ3U N. A. N. A. Patented [2]
BC11-28 DMTWIE2 N. A. N. A. Patented [3]
AC1M1SP5 DMEW5LD N. A. N. A. Patented [3]
PF-04957325 DMPEZKT Inflammation 1A00-CA43.1 Investigative [4]
PF-4957325-00 DMV4P7S Inflammation 1A00-CA43.1 Investigative [5]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 8 (PDE8) TTIS4OW PDE8A_HUMAN Inhibitor [1]

References

1 Therapeutic applications in the cardiovascular field of quinazolinedione derivatives. US8846654.
2 Optically active PDE10 inhibitor. US9493447.
3 Inhibitors of phosphodiesterase 11 (PDE11). US9173884.
4 Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation.Front Pharmacol. 2016 Aug 23;7:259.
5 PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER. PLoS One. 2010 Aug 9;5(8):e12011.