Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPJH6L)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

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Drug(s) Targeting Gamma-secretase subunit APH-1A/1B (APH-1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID28350212-Compound-18	DMH8GC6	Alzheimer disease	8A20	Patented	[1]
PMID28350212-Compound-7	DMUBSFV	Herpes simplex virus infection	1F00	Patented	[1]
PMID28350212-Compound-19	DMI4US6	Alzheimer disease	8A20	Patented	[1]
PMID28350212-Compound-35	DMSKE2O	N. A.	N. A.	Patented	[1]
PMID28350212-Compound-23	DM3MVW1	N. A.	N. A.	Patented	[1]
PMID28350212-Compound-25	DML2VUC	N. A.	N. A.	Patented	[1]
PMID28350212-Compound-22	DMKXZYC	N. A.	N. A.	Patented	[1]
PMID28350212-Compound-13	DMPWYL8	N. A.	N. A.	Patented	[1]
PMID28350212-Compound-1	DMSEIL0	N. A.	N. A.	Patented	[1]
PMID28350212-Compound-36	DM7ULWD	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Gamma-secretase subunit APH-1A/1B (APH-1)	TTZS04O	APH1A_HUMAN-APH1B_HUMAN	Inhibitor	[1]

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References

1	Gamma secretase inhibitors: a patent review (2013 - 2015).Expert Opin Ther Pat. 2017 Jul;27(7):851-866.