Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQB03U)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

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Drug(s) Targeting Cholesterol 24-hydroxylase (CYP46A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
TAK-935	DMOZAMN	Dravet syndrome	8A61.11	Phase 2	[2]
PMID25514969-Compound-Figure3	DM7D12Y	N. A.	N. A.	Patented	[1]
PMID25514969-Compound-8	DM2NVLZ	N. A.	N. A.	Patented	[1]
PMID25514969-Compound-10	DME0XS4	N. A.	N. A.	Patented	[1]
PMID25514969-Compound-9	DMAEZB1	N. A.	N. A.	Patented	[1]
PMID25514969-Compound-Figure2-3	DMUYVOP	N. A.	N. A.	Patented	[1]
PMID25514969-Compound-11	DMUPL0W	N. A.	N. A.	Patented	[1]
PMID25514969-Compound-Figure2-4	DMXSAN7	N. A.	N. A.	Patented	[1]
PMID25514969-Compound-12	DMOE5N0	N. A.	N. A.	Patented	[1]
PMID25514969-Compound-Figure2-2	DMC6S0W	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cholesterol 24-hydroxylase (CYP46A1)	TT4EB85	CP46A_HUMAN	Inhibitor	[1]

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References

1	Imidazo[1,2-a]pyridines as cholesterol 24-hydroxylase (CYP46A1) inhibitors: a patent evaluation (WO2014061676).Expert Opin Ther Pat. 2015 Mar;25(3):373-7.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040983)