General Information of Drug (ID: DMQF62D)

Drug Name
1,2,4-triazole [1,5-a]pyrimidin-7-yl derivative 1 Drug Info
Synonyms PMID27321640-Compound-39
Cross-matching ID
TTD Drug ID
DMQF62D

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tofisopam DMTGNWU Hyperuricaemia 5C55.Y Phase 2 [2]
CP-461 DMEYMTX Inflammatory bowel disease DD72 Phase 2 [3]
ND7001 DMUBTC6 Mood disorder 6A60-6E23 Phase 1 [4]
Pyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazine derivative 1 DMC8935 N. A. N. A. Patented [1]
Pyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazine derivative 2 DM4CSBD N. A. N. A. Patented [1]
Imidazo[5,1-c]pyrido[2,3-e][1,2,4]triazine derivative 2 DMS3ROL N. A. N. A. Patented [1]
Triazolo-pyridine derivative 5 DM1R205 N. A. N. A. Patented [1]
PMID27321640-Compound-58 DM0NYK3 N. A. N. A. Patented [1]
Triazolo-pyridine derivative 4 DM5ZQKS N. A. N. A. Patented [1]
Imidazo[5,1-c]pyrido[2,3-e][1,2,4]triazine derivative 3 DMZ61T8 N. A. N. A. Patented [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 2A (PDE2A) TTJGW1Z PDE2A_HUMAN Inhibitor [1]

References

1 Towards selective phosphodiesterase 2A (PDE2A) inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2016 Aug;26(8):933-46.
2 The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis. J Neural Transm (Vienna). 2010 Nov;117(11):1319-25.
3 Sulindac and its derivatives: a novel class of anticancer agents. Curr Opin Investig Drugs. 2001 May;2(5):677-83.
4 Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures. Neurosignals. 2013;21(3-4):197-212.