Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQT3WJ)

Drug Name

CHLORODEOXYURIDINE Drug Info

Synonyms

Chlorodeoxyuridine; 5-Chlorodeoxyuridine; 5-Chloro-2'-deoxyuridine; CldU; 50-90-8; BRN 0546807; CHEMBL505732; Uridine, 5-chloro-2'-deoxy-; Uridine,5-chloro-2'-deoxy-; 5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione; 5-Chloro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-5-chlorouridine; 5-Chloro-dUrd; 5-Chloro-2 -deoxyuridine; AC1L23DV; AC1Q77TD; SCHEMBL1469771; CTK4J3337; NJCXGFKPQSFZIB-RRKCRQDMSA-N; MolPort-001-814-149

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 65510
CAS Number: CAS 50-90-8
TTD Drug ID: DMQT3WJ

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Mycobacterium Thymidine monophosphate kinase (MycB tmk)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[2]
AMP-PNP	DMTOK1D	Discovery agent	N.A.	Investigative	[3]
2'-deoxythymidine triphosphate	DM9OEJT	Discovery agent	N.A.	Investigative	[2]
Deoxythymidine	DMR90HY	Discovery agent	N.A.	Investigative	[2]
Diphosphate	DMHY30B	Discovery agent	N.A.	Investigative	[2]
Thymidine-5'-Phosphate	DMKM6NQ	Discovery agent	N.A.	Investigative	[2]
P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate	DMM4VWD	Discovery agent	N.A.	Investigative	[4]
3'-Azido-3'-Deoxythymidine-5'-Monophosphate	DMU08MN	Discovery agent	N.A.	Investigative	[2]
5-Hydroxymethyluridine-2'-Deoxy-5'-Monophosphate	DMWVCJ1	Discovery agent	N.A.	Investigative	[2]
BROMODEOXYURIDINE	DM0D7LA	Discovery agent	N.A.	Investigative	[1]
------------------------------------------------------------------------------------


⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mycobacterium Thymidine monophosphate kinase (MycB tmk)	TT5B8AX	KTHY_MYCTU	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial ac... Bioorg Med Chem. 2008 Jun 1;16(11):6075-85.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
4	DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.