Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMR3ZWA)

Drug Name

FCE-25876 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Major depressive disorder	6A70.3	Terminated	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting 5-HT 1 receptor (5HT1R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aryl piperazine derivative 16	DM63XHT	N. A.	N. A.	Patented	[3]
Aryl piperazine derivative 14	DMY8NEL	N. A.	N. A.	Patented	[3]
Aryl piperazine derivative 15	DMRK4IE	N. A.	N. A.	Patented	[3]
RU 24969	DMVW3I9	N. A.	N. A.	Terminated	[4]
Befiperide	DMGAPH1	Anxiety disorder	6B00-6B0Z	Terminated	[5]
SRSS-023	DMUGPDB	Migraine	8A80	Terminated	[6]
Cyanopindolol	DMIBLGH	Discovery agent	N.A.	Investigative	[7]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001389)
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001389)
3	5-HT1A receptor ligands and their therapeutic applications: review of new patents.Expert Opin Ther Pat. 2018 Sep;28(9):679-689.
4	Effect of chronic treatment with 5-HT1 agonist (8-OH-DPAT and RU 24969) and antagonist (isapirone) drugs on the behavioural responses of mice to 5-HT1 and 5-HT2 agonists. Br J Pharmacol. 1986 Oct;89(2):377-84.
5	Behavioral Pharmacology of 5-ht. Paul Bevan, Paul Bevan Duphar, Alexander R. Cools. 2013. Figure(15.2).
6	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019089)
7	The inhibitory effect of serotonin on the spontaneous discharge of suprachiasmatic neurons in hypothalamic slice is mediated by 5-HT(7) receptor. Brain Res Bull. 2001 Mar 1;54(4):395-8.