General Information of Drug (ID: DMRFA5O)

Drug Name
CCNCASKWCRDHSRCC Drug Info
Synonyms CHEMBL524481
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44560055
TTD Drug ID
DMRFA5O

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lanperisone DM4EGPN Musculoskeletal disorder FA00-FC0Z Phase 3 [2]
SIPATRIGINE DMMQ4GC Neurological disorder 6B60 Discontinued in Phase 2 [3]
V-102862 DMR2EUV N. A. N. A. Discontinued in Phase 1 [4]
batrachotoxin DMYH9SU Discovery agent N.A. Investigative [5]
veratridine DMUF8JZ Discovery agent N.A. Investigative [5]
BW-202W92 DMFKXMT Discovery agent N.A. Investigative [3]
CCNCSSKWCRDHSRCC DMBGHTW Discovery agent N.A. Investigative [1]
CCNCSSKWCRAHSRCC DM96YR2 Discovery agent N.A. Investigative [1]
CCACSSKWCRDHSRCC DMSE20Y Discovery agent N.A. Investigative [1]
ZNCCNCSSKWCRDHSRCC DMY2V37 Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Voltage-gated sodium channel alpha Nav1.4 (SCN4A) TT84DRB SCN4A_HUMAN Inhibitor [1]

References

1 Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels. J Biol Chem. 2007 Oct 19;282(42):30699-706.
2 Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels. J Pharmacol Exp Ther. 2005 Dec;315(3):1237-46.
3 Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones. J Med Chem. 2009 May 14;52(9):2694-707.
4 3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers. J Med Chem. 2004 Mar 11;47(6):1547-52.
5 Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin. Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2653-8.