General Information of Drug (ID: DMRNF96)

Drug Name
PMID30247903-Compound-General structure42 Drug Info
Synonyms PMID30247903Compound42
Cross-matching ID
TTD Drug ID
DMRNF96

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Macrocycle derivative 6 DMQ84KW Hepatitis DB97.Z Patented [2]
PMID30107136-Compound-Example12 DMN2K10 Hepatitis DB97.Z Patented [2]
Macrocycle derivative 1 DMN7I9C Hepatitis DB97.Z Patented [2]
Macrocycle derivative 9 DMARU0E Hepatitis DB97.Z Patented [2]
Macrocycle derivative 2 DM5OEQZ Hepatitis DB97.Z Patented [2]
Biaryl compound 1 DMHEAJQ Hepatitis DB97.Z Patented [2]
Macrocycle derivative 3 DMYGFTI Hepatitis DB97.Z Patented [2]
PMID30107136-Compound-Example11 DMD65GU Hepatitis DB97.Z Patented [2]
Macrocycle derivative 8 DMOMTBE Hepatitis DB97.Z Patented [2]
Biaryl compound 2 DMS8VYE Hepatitis DB97.Z Patented [2]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) TT23XQV PDCD1_HUMAN-PD1L1_HUMAN Inhibitor [1]

References

1 Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway.J Med Chem. 2019 Feb 28;62(4):1715-1730.
2 A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678.