Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRP4BM)

Drug Name

MB-104 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Multiple myeloma	2A83	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

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Drug(s) Targeting SLAM family member 7 SLAMF7 (CS1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Elotuzumab	DMEYHG9	Multiple myeloma	2A83	Approved	[3]
PVX-410	DM6DK9A	Multiple myeloma	2A83	Phase 2	[3]
BCMA-CS1 cCAR	DMEPHMR	Multiple myeloma	2A83	Phase 1	[4]
CS1-CAR T Therapy	DMU8OCN	Plasma cell myeloma	2A83.1	Phase 1	[5]
ABBV-838	DMZM0T8	Multiple myeloma	2A83	Phase 1	[6]
UCARTCS1	DM2Y4D7	Multiple myeloma	2A83	Phase 1	[7]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT03710421) CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory CS1 Positive Multiple Myeloma. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Mustang Bio.
3	Market watch: Upcoming catalysts in Q2 2015. Nat Rev Drug Discov. 2015 Apr;14(4):228.
4	ClinicalTrials.gov (NCT04156269) BCMA-CS1 Compound CAR (cCAR) T Cells for Relapsed/Refractory Multiple Myeloma. U.S. National Institutes of Health.
5	ClinicalTrials.gov (NCT03710421) CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory Multiple Myeloma
6	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
7	ClinicalTrials.gov (NCT04142619) Study Evaluating Safety and Efficacy of UCART Targeting CS1 in Patients With Relapsed/Refractory Multiple Myeloma (MELANI-01). U.S. National Institutes of Health.