Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRQUH4)

Drug Name

NI-0801 Drug Info

Synonyms

Anti-interferon inducible protein 10, NovImmune

Indication

Disease Entry	ICD 11	Status	REF
Autoimmune diabetes	5A10	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting C-X-C motif chemokine 10 (CXCL10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BMS-936557	DMUTS1W	Immune System disease	4A01-4B41	Phase 2	[3]
MDX-1100	DM0EZWI	Crohn disease	DD70	Phase 2	[4]
Anti-IP10	DMVRNAO	Crohn disease	DD70	Phase 2	[3]
JT02	DMXTKCR	Inflammatory bowel disease	DD72	Phase 2	[5]
NG-641	DMITVHM	Solid tumour/cancer	2A00-2F9Z	Phase 1	[6]
N-Methylleucine	DM9AGCV	Discovery agent	N.A.	Investigative	[7]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT01430429) Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody. U.S. National Institutes of Health.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029267)
3	Anti-IP-10 antibody (BMS-936557) for ulcerative colitis: a phase II randomised study. Gut. 2014 Mar;63(3):442-50.
4	A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis. Arthritis Rheum. 2012 Jun;64(6):1730-9.
5	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
6	Clinical pipeline report, company report or official report of PsiOxus Therapeutics.
7	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.