General Information of Drug (ID: DMRYQBE)

Drug Name
AS-1406 Drug Info
Synonyms Theranase; HuHMFG1-huRNase; Targeted apoptosis (RNase), Antisoma
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Terminated [1]
Cross-matching ID
TTD Drug ID
DMRYQBE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Ribonuclease (RNase)
Drug Name Drug ID Indication ICD 11 Highest Status REF
NTO-1151 DMRYLBW Cervical cancer 2C77.0 Phase 2 [3]
Ranpirnase DMM15RI Lung cancer 2C25.0 Phase 2 [4]
MazF gene therapy DMSZ8HT Human immunodeficiency virus-1 infection 1C62 Phase 1 [5]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ribonuclease (RNase) TTRBUYN NOUNIPROTAC Modulator [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012949)
2 WO patent application no. 2005,0657,17, Liquid formulations of antibody conjugates.
3 Clinical pipeline report, company report or official report of Nanotherapeutics.
4 Ranpirnase (Onconase), a cytotoxic amphibian ribonuclease, manipulates tumour physiological parameters as a selective killer and a potential enhancer for chemotherapy and radiation in cancer therapy.Expert Opin Biol Ther. 2008 Jun;8(6):813-27.
5 Clinical pipeline report, company report or official report of Takara Bio.