Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRZHV6)

Drug Name
PF-06873600 Drug Info
Synonyms QIEKHLDZKRQLLN-FOIQADDNSA-N; SCHEMBL19857421; HY-114177; CS-0078633
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Phase 1 [1]
Cross-matching ID
PubChem CID
134247638
CAS Number
CAS 2185857-97-8
TTD Drug ID
DMRZHV6

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Cyclin-dependent kinase (CDK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
R-roscovitine DMSH108 Non-small-cell lung cancer 2C25.Y Phase 2 [2]
Flavopiridol DMKSUOI Acute myeloid leukaemia 2A60 Phase 2 [3]
TG02 DMZFIGQ Anaplastic astrocytoma 2A00.0 Phase 1/2 [1]
PMID26161698-Compound-44 DM8UPO3 N. A. N. A. Patented [4]
Purine derivative 4 DMYD5SQ N. A. N. A. Patented [4]
Indole-based analog 12 DM1CNRH N. A. N. A. Patented [4]
PMID26161698-Compound-10 DMXVCHZ N. A. N. A. Patented [4]
BS-194 DMLXFHD Solid tumour/cancer 2A00-2F9Z Investigative [5]
⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cyclin-dependent kinase (CDK) TTMBO1Z NOUNIPROTAC Inhibitor [1]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Therapeutic efficacy of seliciclib in combination with ionizing radiation for human nasopharyngeal carcinoma.Clin Cancer Res. 2009 Jun 1;15(11):3716-24.
3 Pharma & Vaccines. Product Development Pipeline. April 29 2009.
4 Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014).Expert Opin Ther Pat. 2015;25(9):953-70.
5 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8176).