Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMS0L6J)

Drug Name
NY-ESO-TCR Drug Info
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Phase 1/2 [1]
Multiple myeloma 2A83 Phase 1/2 [1]
Myxoid round cell liposarcoma 2B59 Phase 1/2 [1]
Ovarian cancer 2C73 Phase 1/2 [1]
Synovial sarcoma 2B5A Phase 1/2 [1]
Cross-matching ID
TTD Drug ID
DMS0L6J

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting T-cell receptor (TCR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tebentafusp DMUJ1WV Gastric cancer 2B72 Approved [1]
RGI-2001 DM4AC2F Graft-versus-host disease 4B24 Phase 2 [2]
IR502 DMW2IF9 Plaque psoriasis EA90.0 Phase 2 [3]
SAR444200 DM7J5H0 Aggressive cancer 2A00-2F9Z Phase 2 [4]
TOL-101 DM6AXV9 Multiple sclerosis 8A40 Phase 1/2 [5]
MAGE-A10 TCR DM6H3YS Bladder cancer 2C94 Phase 1/2 [1]
AFP TCR DMHBUMZ Hepatocellular carcinoma 2C12.02 Phase 1 [1]
BPX-701 DMYERSD Acute myeloid leukaemia 2A60 Phase 1 [1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
T-cell receptor (TCR) TT7AKW1 NOUNIPROTAC CAR-T-Cell-Therapy [1]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Pharmacologic expansion of donor-derived, naturally occurring CD4(+)Foxp3(+) regulatory T cells reduces acute graft-versus-host disease lethality without abrogating the graft-versus-leukemia effect in murine models. Biol Blood Marrow Transplant. 2011 Aug;17(8):1154-68.
3 WO patent application no. 2004,0677,06, Production of multimeric proteins.
4 Clinical pipeline report, company report or official report of Sanofi
5 First-in-Human Study of the Safety and Efficacy of TOL101 Induction to Prevent Kidney Transplant Rejection. Am J Transplant. 2014 June; 14(6): 1346-1355.