Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMS5DHY)

Drug Name

Cystamine Drug Info

Synonyms

Cystamine dihydrochloride; 56-17-7; 2,2'-Disulfanediyldiethanamine dihydrochloride; Ethanamine, 2,2'-dithiobis-, dihydrochloride; Cystamin dihydrochloride; Bis(2-aminoethyl) disulfide dihydrochloride; USAF CB-34; 2-Aminoethyl disulfide dihydrochloride; Cystamine 2HCL; UNII-I90T518457; EINECS 200-260-7; NSC 39322; 2,2'-Dithiodi(ethylammonium) dichloride; Decarboxycystine dihydrochloride; 2,2'-Dithio-bis-(ethylamine) dihydrochloride; Usafcb-34; MFCD00012905; 2-Aminoethyl Dislufide Dihydrochloride

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2915
ChEBI ID: CHEBI:78757
CAS Number: CAS 51-85-4
TTD Drug ID: DMS5DHY

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Glutamate--cysteine ligase modifier (GCLM)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
N-Formylmethionine	DM7GBDX	Discovery agent	N.A.	Investigative	[2]
Buthionine sulfoximine	DMJ46CB	Malaria	1F40-1F45	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glutamate--cysteine ligase modifier (GCLM)	TTNFESW	GSH0_HUMAN	Inhibitor	[1]

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References

1	The gamma-glutamylcysteine synthetase of Onchocerca volvulus. Mol Biochem Parasitol. 2000 Dec;111(2):243-51.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3	Novel molecular targets for antimalarial chemotherapy. Int J Antimicrob Agents. 2007 Jul;30(1):4-10.