Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMSTL12)

Drug Name

RG7232 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Dyslipidemia	5C80-5C81	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Discontinued Drug(s)

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Drug(s) Targeting ATP-binding cassette transporter A1 (ABCA1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Probucol	DMVZQ2M	Coronary artery disease	BA80	Approved	[2]
RG-7273	DMXMQAT	Lipid metabolism disorder	5C52.Z	Discontinued in Phase 1	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
ATP-binding cassette transporter A1 (ABCA1)	TTJW1GN	ABCA1_HUMAN	Modulator	[1]

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References

1	Analysis of "On/Off" Kinetics of a CETP Inhibitor Using a Mechanistic Model of Lipoprotein Metabolism and Kinetics. CPT Pharmacometrics Syst Pharmacol. 2015 Aug;4(8):465-73.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 756).