Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMSZ8HT)

Drug Name

MazF gene therapy Drug Info

Synonyms

MazF gene therapy (HIV)

Indication

Disease Entry	ICD 11	Status	REF
Human immunodeficiency virus-1 infection	1C62	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Discontinued Drug(s)

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Drug(s) Targeting Ribonuclease (RNase)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
NTO-1151	DMRYLBW	Cervical cancer	2C77.0	Phase 2	[3]
Ranpirnase	DMM15RI	Lung cancer	2C25.0	Phase 2	[4]
AS-1406	DMRYQBE	Solid tumour/cancer	2A00-2F9Z	Terminated	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Clinical pipeline report, company report or official report of Takara Bio.
2	Clinical pipeline report, company report or official report of Takara Bio.
3	Clinical pipeline report, company report or official report of Nanotherapeutics.
4	Ranpirnase (Onconase), a cytotoxic amphibian ribonuclease, manipulates tumour physiological parameters as a selective killer and a potential enhancer for chemotherapy and radiation in cancer therapy.Expert Opin Biol Ther. 2008 Jun;8(6):813-27.
5	WO patent application no. 2005,0657,17, Liquid formulations of antibody conjugates.