General Information of Drug (ID: DMTCEFV)

Drug Name
Glycinamid Drug Info
Synonyms
Glycinamide; 2-Aminoacetamide; 598-41-4; Glycine amide; Acetamide, 2-amino-; GLYCINAMID; AMINOMETHYLAMIDE; 2-Amino-Acetamide; CHEBI:42843; BEBCJVAWIBVWNZ-UHFFFAOYSA-N; Glycinamide HCl; AI3-60342; aminoacetamide; glycineamide; glycinamidehcl; glycine-amide; glycine imine; Glycinimidic acid; alpha-aminoacetamide; EINECS 209-932-4; GlyNH2; 2-Aminoacetamide #; Gly-NH2; Glycineamide, G-NH2; AC1L2AXY; H2NCH2CONH2; Glycine amide hydrobromide; AC1Q53MT; CHEMBL86954; 598-41-4 (Parent); DTXSID1060508; 1668-10-6 (hydrochloride); CTK1H1328; CTK1D7741
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
69020
ChEBI ID
CHEBI:42843
CAS Number
CAS 598-41-4
TTD Drug ID
DMTCEFV

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CIPEMASTAT DM803GL Rheumatoid arthritis FA20 Phase 3 [2]
GM6001 DM7V9CT Corneal ulcer 9A76 Discontinued in Phase 2 [3]
SC-44463 DMBPNKT N. A. N. A. Terminated [4]
BB-1101 DM7GH5Z Multiple sclerosis 8A40 Terminated [5]
MMI270 DM38N2K Discovery agent N.A. Investigative [6]
IK-862 DMJA4UE Discovery agent N.A. Investigative [7]
2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide DMCNV5J Discovery agent N.A. Investigative [8]
SL422 DM3I2US Discovery agent N.A. Investigative [9]
[2-(Biphenyl-4-sulfonyl)phenyl]acetic Acid DM37C25 Discovery agent N.A. Investigative [8]
N-Hydroxy-2-(4-phenoxy-benzenesulfonyl)benzamide DM4VADN Discovery agent N.A. Investigative [8]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Matrix metalloproteinase-8 (MMP-8) TTGA1IV MMP8_HUMAN Inhibitor [1]

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2 Matrix metalloproteinase inhibition lowers mortality and brain injury in experimental pneumococcal meningitis. Infect Immun. 2014 Apr;82(4):1710-8.
3 Hydroxamate inhibitors of human gelatinase B (92 kDa), Bioorg. Med. Chem. Lett. 5(4):349-352 (1995).
4 Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivati... J Med Chem. 2001 Oct 11;44(21):3347-50.
5 New alpha-substituted succinate-based hydroxamic acids as TNFalpha convertase inhibitors. J Med Chem. 1999 Nov 18;42(23):4890-908.
6 Design, synthesis, and biological evaluation of potent thiazine- and thiazepine-based matrix metalloproteinase inhibitors. J Med Chem. 1999 Nov 4;42(22):4547-62.
7 Discovery of gamma-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor alpha converting enzyme: design, synthesis, and structu... J Med Chem. 2002 Nov 7;45(23):4954-7.
8 Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhib... J Med Chem. 2009 Oct 22;52(20):6347-61.
9 Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro and in vivo. J Med Chem. 2001 Aug 2;44(16):2636-60.