Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTMS3L)

Drug Name

Barucainide Drug Info

Synonyms

Barucainide; UNII-14NFL30YOH; 79784-22-8; 14NFL30YOH; Barucainidum; Barucainide [INN]; Barucainid; AC1Q1QCZ; AC1L3TX5; SCHEMBL2110723; CHEMBL2105905; DTXSID60229912; ZINC3643459; 4-Benzyl-1,3-dihydro-7-(4-(isopropylamino)butoxy)-6-methylfuro(3,4-c)pyridine; 4-[(4-benzyl-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-yl)oxy]-N-propan-2-ylbutan-1-amine

Indication

Disease Entry	ICD 11	Status	REF
Heart arrhythmia	BC65	Terminated	[1]

Cross-matching ID

PubChem CID: 146795
CAS Number: CAS 79784-22-8
TTD Drug ID: DMTMS3L

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting E3 ubiquitin-protein ligase COP1 (RFWD2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quinine	DMSWYF5	Malaria	1F40-1F45	Approved	[3]
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[3]
Propafenone	DMPIBJK	Tachyarrhythmias	BC71	Approved	[3]
Flecainide	DMSQDLE	Tachyarrhythmias	BC71	Approved	[3]
Tocainide	DMYNMDP	Ventricular arrhythmias	BC71	Approved	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
E3 ubiquitin-protein ligase COP1 (RFWD2)	TT05DLS	COP1_HUMAN	Modulator	[2]
Voltage-gated sodium channel (Nav)	TTIG65Q	NOUNIPROTAC	Modulator	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000197)
2	Barucainide, a novel class Ib antiarrhythmic agent with a slow kinetic property: electrophysiologic observations in isolated canine and rabbit cardiac muscle. Am Heart J. 1990 May;119(5):1050-60.
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.