General Information of Drug (ID: DMU4Q8C)

Drug Name
2beta,3alpha-dihydroxyurs-12-en-28-oic acid Drug Info
Synonyms
CHEMBL574993; SCHEMBL4456541; (2beta,3alpha)-2,3-Dihydroxy-urs-12-en-28-oic acid; BDBM50346702; ZINC49708319; 856012-03-8; 2beta,3alpha-Dihydroxyurs-12-ene-28-oic acid; 012A038; Adbeta,3a)-2,3-dihydroxy-urs-12-en-28-oic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
45481653
TTD Drug ID
DMU4Q8C

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
URSOLIC ACID DM4SOAW Metabolic syndrome x 5C50-5D2Z Phase 2 [2]
JTT-651 DMGP42Q Type-2 diabetes 5A11 Discontinued in Phase 1 [3]
L-serine-O-phosphate DMTJ1NH Discovery agent N.A. Investigative [4]
Beta-D-Glucose DM5IHYP Discovery agent N.A. Investigative [4]
Indirubin-5-sulfonate DM08VHZ Discovery agent N.A. Investigative [4]
Inosinic Acid DMLR86H Discovery agent N.A. Investigative [4]
Alpha-D-Glucose-6-Phosphate DMR0EVN Discovery agent N.A. Investigative [4]
N'-Pyridoxyl-Lysine-5'-Monophosphate DM3ZHBO Discovery agent N.A. Investigative [4]
OLEANOLIC_ACID DMWDMJ3 Discovery agent N.A. Investigative [5]
Oleanonic acid DMYPJC3 Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glycogen phosphorylase muscle form (GP) TTZHY6R PYGM_HUMAN Inhibitor [1]

References

1 Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase. J Nat Prod. 2008 Nov;71(11):1877-80.
2 Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase. J Nat Prod. 2009 Aug;72(8):1414-8.
3 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026877)
4 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
5 Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystal... J Med Chem. 2008 Jun 26;51(12):3540-54.