General Information of Drug (ID: DMU6R3O)

Drug Name
CLG561 Drug Info
Indication
Disease Entry ICD 11 Status REF
Geographic retinal atrophy 9B78.9 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMU6R3O

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Complement factor P (CFP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ALXN1820 DMNZOJ3 Sickle-cell disorder 3A51 Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement factor P (CFP) TTLA0VS PROP_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT02515942) CLG561 Proof-of-Concept Study as a Monotherapy and in Combination With LFG316 in Subjects With Geographic Atrophy (GA). U.S. National Institutes of Health.
2 Complement inhibition as a therapeutic strategy in retinal disorders. Expert Opin Biol Ther. 2019 Apr;19(4):335-342.
3 Clinical pipeline report, company report or official report of Alexion