Details of the Drug

General Information of Drug (ID: DMU6R3O)

• Drug Name: CLG561

Indication

Disease Entry	ICD 11	Status	REF
Geographic retinal atrophy	9B78.9	Phase 2	[1]

• Drug Type: Antibody
• Cross-matching ID: TTD ID: D4LJO9

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Complement factor P (CFP)	TTLA0VS	PROP_HUMAN	Inhibitor	[2]

References

• [1] ClinicalTrials.gov (NCT02515942) CLG561 Proof-of-Concept Study as a Monotherapy and in Combination With LFG316 in Subjects With Geographic Atrophy (GA). U.S. National Institutes of Health.
• [2] Complement inhibition as a therapeutic strategy in retinal disorders. Expert Opin Biol Ther. 2019 Apr;19(4):335-342.