General Information of Drug (ID: DMUR0TF)

Drug Name
Tu-514 Drug Info
Synonyms
TU-514; 1,5-ANHYDRO-2-C-(CARBOXYMETHYL-N-HYDROXYAMIDE)-2-DEOXY-3-O-MYRISTOYL-D-GLUCITOL; TUX; 1xxe; 2go4; AC1L9MVN; CHEMBL1236446; DB01991; 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-3-O-tetradecanoyl-D-glucitol; [(2R,3S,4R,5S)-3-hydroxy-5-[2-(hydroxyamino)-2-oxoethyl]-2-(hydroxymethyl)oxan-4-yl] tetradecanoate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
449223
TTD Drug ID
DMUR0TF

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Preclinical Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
LpxC-1 DMV1A25 Acinetobacter baumannii infection CA40.0Y Preclinical [2]
RC-01 DM4FNWO Gram-negative bacterial infection 1B74-1G40 Terminated [3]
MYRISTIC ACID DMYX0BL Discovery agent N.A. Investigative [4]
Cacodylate Ion DMK4XLD Discovery agent N.A. Investigative [1]
Palmitoleic Acid DM4W5X8 Discovery agent N.A. Investigative [1]
3-(heptyloxy)benzoic acid DMQZU9G Discovery agent N.A. Investigative [4]
BB-78484 DMFBN9O Discovery agent N.A. Investigative [5]
BB-78485 DMJKA3F Discovery agent N.A. Investigative [5]
⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pseudomonas UDP-3-O-acyl-GlcNAc deacetylase (Pseudo lpxC) TT0OFWN LPXC_PSEAE Inhibitor [1]

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2 Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance. Nat Rev Drug Discov. 2017 Jul;16(7):457-471.
3 The global preclinical antibacterial pipeline. Nat Rev Microbiol. 2020 May;18(5):275-285.
4 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
5 Antibacterial activities and characterization of novel inhibitors of LpxC. Antimicrob Agents Chemother. 2002 Jun;46(6):1793-9.