General Information of Drug (ID: DMV1A25)

Drug Name
LpxC-1 Drug Info
Indication
Disease Entry ICD 11 Status REF
Acinetobacter baumannii infection CA40.0Y Preclinical [1]
Cross-matching ID
TTD Drug ID
DMV1A25

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
RC-01 DM4FNWO Gram-negative bacterial infection 1B74-1G40 Terminated [2]
MYRISTIC ACID DMYX0BL Discovery agent N.A. Investigative [3]
Cacodylate Ion DMK4XLD Discovery agent N.A. Investigative [4]
Palmitoleic Acid DM4W5X8 Discovery agent N.A. Investigative [4]
3-(heptyloxy)benzoic acid DMQZU9G Discovery agent N.A. Investigative [3]
BB-78484 DMFBN9O Discovery agent N.A. Investigative [5]
BB-78485 DMJKA3F Discovery agent N.A. Investigative [5]
Tu-514 DMUR0TF Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Pseudomonas UDP-3-O-acyl-GlcNAc deacetylase (Pseudo lpxC) TT0OFWN LPXC_PSEAE Inhibitor [1]

References

1 Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance. Nat Rev Drug Discov. 2017 Jul;16(7):457-471.
2 The global preclinical antibacterial pipeline. Nat Rev Microbiol. 2020 May;18(5):275-285.
3 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
4 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
5 Antibacterial activities and characterization of novel inhibitors of LpxC. Antimicrob Agents Chemother. 2002 Jun;46(6):1793-9.