Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMV27SP)

Drug Name

Panobacumab Drug Info

Synonyms

KBPA-101; Human monoclonal antibody (Pseudomonas aeruginosa), Berna; MAb (Pseudomonas aeruginosa), Berna

Indication

Disease Entry	ICD 11	Status	REF
Hospital-acquired pneumonia	CA40.Z	Phase 2	[1]
Ventilator-associated pneumonia	PK81.0	Phase 2	[1]
Pseudomonas infection	1B92	Phase 1/2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Pseudomonas Lipopolysaccharide (Pseudo LPS)	TT4ESMB	NOUNIPROTAC	Modulator	[2]

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References

1	ClinicalTrials.gov (NCT00851435) Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa. U.S. National Institutes of Health.
2	Antibacterial antibodies gain traction. Nat Rev Drug Discov. 2015 Nov;14(11):737-8.