Details of the Drug

General Information of Drug (ID: DMV27SP)

Drug Name

Panobacumab

Synonyms

KBPA-101; Human monoclonal antibody (Pseudomonas aeruginosa), Berna; MAb (Pseudomonas aeruginosa), Berna

Indication

Disease Entry	ICD 11	Status	REF
Hospital-acquired pneumonia	CA40.Z	Phase 2	[1]
Ventilator-associated pneumonia	PK81.0	Phase 2	[1]
Pseudomonas infection	1B92	Phase 1/2	[1]
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Drug Type

Monoclonal antibody

Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Pseudomonas Lipopolysaccharide (Pseudo LPS)	TT4ESMB	NOUNIPROTAC	Modulator	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT00851435) Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa. U.S. National Institutes of Health.
2	Antibacterial antibodies gain traction. Nat Rev Drug Discov. 2015 Nov;14(11):737-8.