General Information of Drug (ID: DMV574J)

Drug Name
CSL312 Drug Info
Synonyms Garadacimab
Indication
Disease Entry ICD 11 Status REF
Hereditary angioedema 4A00.14 Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMV574J

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ION547 DMVNKNJ Thrombosis DB61-GB90 Phase 1 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor XII (F12) TTMXD0O FA12_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04656418) CSL312 (Garadacimab) in the Prevention of Hereditary Angioedema Attacks. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of CSL Behring.
3 ClinicalTrials.gov (NCT04934891) A Double-Blind, Placebo-Controlled, Dose-Escalation Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of ION547 Administered Subcutaneously to Healthy Subjects. U.S.National Institutes of Health.