Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMV9QGW)

Drug Name
BPX-601 Drug Info
Indication
Disease Entry ICD 11 Status REF
Gastric adenocarcinoma 2B72 Phase 1/2 [1]
Pancreatic cancer 2C10 Phase 1/2 [1]
Prostate cancer 2C82.0 Phase 1/2 [1]
Cross-matching ID
TTD Drug ID
DMV9QGW

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Prostate stem cell antigen (PSCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Anti-PSCA mab DMJPZDC Pancreatic cancer 2C10 Phase 2 [2]
CAR-T cells targeting PSCA DMU4G9J Pancreatic cancer 2C10 Phase 1 [3]
CAR-T cells targeting PSCA DMU4G9J Pancreatic cancer 2C10 Phase 1 [4]
GEM3PSCA DM3GSPR Non-small-cell lung cancer 2C25 Phase 1 [5]
MB-105 DMVGTP6 Prostate cancer 2C82.0 Phase 1 [6]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostate stem cell antigen (PSCA) TT9T4AV PSCA_HUMAN CAR-T-Cell-Therapy [1]

References

1 ClinicalTrials.gov (NCT02744287) Use of Ligand-Inducible Autologous T Cells Engineered to Target PSCA on Tumor Cells in Selected Advanced Solid Tumors
2 Phase I rapid dose-escalation study of AGS-1C4D4, a human anti-PSCA (prostate stem cell antigen) monoclonal antibody, in patients with castration-resistant prostate cancer: a PCCTC trial. Cancer Chemother Pharmacol. 2012 Mar;69(3):763-71.
3 ClinicalTrials.gov (NCT03267173) Evaluate the Safety and Efficacy of CAR-T in the Treatment of Pancreatic Cancer.
4 ClinicalTrials.gov (NCT03198052) HER2/Mesothelin/Lewis-Y/PSCA/MUC1/PD-L1/CD80/86-CAR-T Cells Immunotherapy Against Cancers
5 Clinical pipeline report, company report or official report of Gemoab.
6 Clinical pipeline report, company report or official report of Mustang Bio.