Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVGAI4)

Drug Name

DYN101 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Congenital structural myopathy	8C72.0	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting DNM2 messenger RNA (DNM2 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
IONIS-DNM2-2.5Rx	DM5LM3O	Centronuclear myopathy	8C72.01	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT04033159) A Phase 1/2 Trial on the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Exploratory Efficacy of DYN101 in Patients >= 16 Years of Age With Centronuclear Myopathies Caused by Mutations in DNM2 or MTM1. U.S.National Institutes of Health.
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2023. Adis Insight
3	Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.