General Information of Drug (ID: DMVGAI4)

Drug Name
DYN101
Indication
Disease Entry ICD 11 Status REF
Congenital structural myopathy 8C72.0 Phase 1/2 [1]
Drug Type
Antisense oligonucleotide
Cross-matching ID
TTD ID
D1ZAW4

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNM2 messenger RNA (DNM2 mRNA) TTVRA5G DYN2_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04033159) A Phase 1/2 Trial on the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Exploratory Efficacy of DYN101 in Patients >= 16 Years of Age With Centronuclear Myopathies Caused by Mutations in DNM2 or MTM1. U.S.National Institutes of Health.
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2023. Adis Insight