Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVQJOS)

Drug Name

PXS-25 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Fibrosis	GA14-GC01	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Preclinical Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting CI Man-6-P receptor (IGF2R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Juvidex	DMZKYNO	Sarcoidosis	4B20.5	Phase 2	[2]
EP-128504	DMJEKQM	Solid tumour/cancer	2A00-2F9Z	Preclinical	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-beta1. Am J Physiol Renal Physiol.2011 Jul;301(1):F84-93.
2	Hypertrophic Scarring and Keloids: Pathomechanisms and Current and Emerging Treatment Strategies. Mol Med. 2011 Jan-Feb; 17(1-2): 113-125.
3	The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach. Mol Cancer Ther. 2005 May;4(5):761-71.