Details of the Drug

General Information of Drug (ID: DMVQJOS)

Drug Name
PXS-25
Indication
Disease Entry ICD 11 Status REF
Fibrosis GA14-GC01 Phase 1 [1]
Cross-matching ID
TTD ID
D00VFH

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CI Man-6-P receptor (IGF2R) TTPNE41 MPRI_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-beta1. Am J Physiol Renal Physiol.2011 Jul;301(1):F84-93.