Details of the Drug-Related molecule(s) Interaction Atlas

RU 24969 Drug Info

RU 24969; 66611-26-5; RU-24969; 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole; UNII-2ISE72RACC; 2ISE72RACC; CHEMBL18785; 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; RU-24,969; KRVMLPUDAOWOGN-UHFFFAOYSA-N; NCGC00024867-01; Tocris-0912; GTPL23; Biomol-NT_000116; AC1Q4F1Q; SCHEMBL2359264; AC1L337E; BPBio1_000177; CHEBI:92005; BDBM81498; CTK1J4546; DTXSID40276045; MolPort-003-983-322; ZINC2568243; PDSP1_001623; PDSP2_001607; PDSP2_001601; PDSP1_001617; AKOS005135871; MCULE-3532976182; CS-3218; CAS_108028; API0006969

Cross-matching ID

PubChem CID

108029

ChEBI ID

CHEBI:92005

CAS Number

CAS 66611-26-5

TTD Drug ID

DMVW3I9

General Information of Drug (ID: DMVW3I9)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting 5-HT 1 receptor (5HT1R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aryl piperazine derivative 16	DM63XHT	N. A.	N. A.	Patented	[2]
Aryl piperazine derivative 14	DMY8NEL	N. A.	N. A.	Patented	[2]
Aryl piperazine derivative 15	DMRK4IE	N. A.	N. A.	Patented	[2]
Befiperide	DMGAPH1	Anxiety disorder	6B00-6B0Z	Terminated	[3]
FCE-25876	DMR3ZWA	Major depressive disorder	6A70.3	Terminated	[4]
SRSS-023	DMUGPDB	Migraine	8A80	Terminated	[5]
Cyanopindolol	DMIBLGH	Discovery agent	N.A.	Investigative	[6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Effect of chronic treatment with 5-HT1 agonist (8-OH-DPAT and RU 24969) and antagonist (isapirone) drugs on the behavioural responses of mice to 5-HT1 and 5-HT2 agonists. Br J Pharmacol. 1986 Oct;89(2):377-84.
2	5-HT1A receptor ligands and their therapeutic applications: review of new patents.Expert Opin Ther Pat. 2018 Sep;28(9):679-689.
3	Behavioral Pharmacology of 5-ht. Paul Bevan, Paul Bevan Duphar, Alexander R. Cools. 2013. Figure(15.2).
4	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001389)
5	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019089)
6	The inhibitory effect of serotonin on the spontaneous discharge of suprachiasmatic neurons in hypothalamic slice is mediated by 5-HT(7) receptor. Brain Res Bull. 2001 Mar 1;54(4):395-8.