Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVYG0U)

Drug Name	PMID28594589-Compound-TABLE3C2 Drug Info
Cross-matching ID	TTD Drug ID DMVYG0U

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting ERK activator kinase (MEK)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ARRY-162	DM1P6FR	Melanoma	2C30	Approved	[2]
NFX-179	DM77XQT	Neurofibromatosis 1	LD2D.10	Phase 2	[3]
HL-085	DMJDVCW	Melanoma	2C30	Phase 1/2	[4]
RG7304	DMGFAVQ	Solid tumour/cancer	2A00-2F9Z	Phase 1	[5]
GDC-0623	DMDY08K	Solid tumour/cancer	2A00-2F9Z	Phase 1	[6]
BI 3011441	DMFJGUL	Solid tumour/cancer	2A00-2F9Z	Phase 1	[7]
Pyridinone compound 1	DM2GR5Q	N. A.	N. A.	Patented	[1]
Quinazolines and azaquinazoline derivative 1	DME24BI	N. A.	N. A.	Patented	[1]
Benzoheterocyclic compound 1	DM3K25J	N. A.	N. A.	Patented	[1]
Benzoimidazole derivative 1	DMUJFCK	N. A.	N. A.	Patented	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	MEK inhibitors in oncology: a patent review (2015-Present).Expert Opin Ther Pat. 2017 Aug;27(8):887-906.
2	2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
3	Clinical pipeline report, company report or official report of NFlection Therapeutics
4	Current Development Status of MEK Inhibitors. Molecules. 2017 Sep 26;22(10):1551.
5	Clinical pipeline report, company report or official report of Roche.
6	Clinical pipeline report, company report or official report of Genentech (2011).
7	Clinical pipeline report, company report or official report of Boehringer Ingelheim.