Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMWMIRL)

Drug Name
Alisporivir Drug Info
Synonyms DEB-025; Debio-025; HCV infection therapy, Debiopharm/Novartis; HIV infection therapy, Debiopharm
Indication
Disease Entry ICD 11 Status REF
Hepatitis C virus infection 1E51.1 Phase 3 [1]
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [2] , [3]
Severe acute respiratory syndrome (SARS) 1D65 Investigative [3]
Therapeutic Class
Antiviral Agents
Cross-matching ID
PubChem CID
11513676
CAS Number
CAS 254435-95-5
TTD Drug ID
DMWMIRL

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HUMAN cyclophilin A (CYPA) TTS41ER PPIA_HUMAN Inhibitor [2] , [3]

References

1 ClinicalTrials.gov (NCT01500772) Alisporivir With PEG and RBV in Protease Inhibitor (PI) Treatment Failure Patients With Chronic Hepatitis C
2 Therapeutic options for the 2019 novel coronavirus (2019-nCoV). Nat Rev Drug Discov. 2020 Mar;19(3):149-150.
3 Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.