Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXACM2)

Drug Name

Anti-RON receptor mabs Drug Info

Synonyms

AV-368 series; Hu-07F01; Hu-29B06; Anti-RON receptor mAbs (cancer); Anti-RON receptor mAbs (cancer), AVEO Pharmaceuticals; Anti-RON receptor mAbs (cancer), Centocor Ortho Biotech

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]

Cross-matching ID

TTD Drug ID: DMXACM2

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Macrophage-stimulating protein receptor (RON)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
MK-2461	DM21WBH	Alzheimer disease	8A20	Phase 1/2	[2]
ABC-7	DM2AIE9	Solid tumour/cancer	2A00-2F9Z	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Macrophage-stimulating protein receptor (RON)	TTBQ3OC	RON_HUMAN	Not Available	[1]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1816).
2	MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor. Cancer Res. 2010 Feb 15;70(4):1524-33.