Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXFY4P)

Drug Name

PMID12614873C2b-1 Drug Info

Synonyms

GTPL3696

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting C-C chemokine receptor (CCR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
viral macrophage inflammatory protein-II	DMAXOPS	Discovery agent	N.A.	Investigative	[2]
CP-481,715	DMZT7C1	Discovery agent	N.A.	Investigative	[3]
UCB35625	DMQB8C3	Discovery agent	N.A.	Investigative	[4]
VT-224	DMB7I0A	Inflammation	1A00-CA43.1	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Structure-activity relationships of xanthene carboxamides, novel CCR1 receptor antagonists. Bioorg Med Chem. 2003 Mar 20;11(6):875-84.
2	A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus. Science. 1997 Sep 12;277(5332):1656-9.
3	CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases. J Biol Chem. 2003 Oct 17;278(42):40473-80.
4	A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry. J Biol Chem. 2000 Aug 25;275(34):25985-92.
5	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 67).