Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXRU72)

Drug Name
SEP-227900 Drug Info
Indication
Disease Entry ICD 11 Status REF
Cognitive impairment 6D71 Terminated [1]
Cross-matching ID
PubChem CID
7141881
TTD Drug ID
DMXRU72

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting D-amino acid oxidase (DAO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
TAK-831 DMWPSJR Friedreich's ataxia 8A03.10 Phase 2 [2]
TAK-831 DMWPSJR Friedreich's ataxia 8A03.10 Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
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Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
D-amino acid oxidase (DAO) TT7Y3EJ OXDA_HUMAN Inhibitor [1]

References

1 The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors. Open Med Chem J. 2010; 4: 3-9.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics (PK/TO/PD) Relationship of D-Amino Acid Oxidase Inhibitor, TAK-831 in Mice. Pharm Res. 2020 Aug 5;37(8):164.