Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXVCHZ)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Cyclin-dependent kinase (CDK)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
R-roscovitine	DMSH108	Non-small-cell lung cancer	2C25.Y	Phase 2	[2]
Flavopiridol	DMKSUOI	Acute myeloid leukaemia	2A60	Phase 2	[3]
TG02	DMZFIGQ	Anaplastic astrocytoma	2A00.0	Phase 1/2	[4]
PF-06873600	DMRZHV6	Breast cancer	2C60-2C65	Phase 1	[4]
PMID26161698-Compound-44	DM8UPO3	N. A.	N. A.	Patented	[1]
Purine derivative 4	DMYD5SQ	N. A.	N. A.	Patented	[1]
Indole-based analog 12	DM1CNRH	N. A.	N. A.	Patented	[1]
BS-194	DMLXFHD	Solid tumour/cancer	2A00-2F9Z	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014).Expert Opin Ther Pat. 2015;25(9):953-70.
2	Therapeutic efficacy of seliciclib in combination with ionizing radiation for human nasopharyngeal carcinoma.Clin Cancer Res. 2009 Jun 1;15(11):3716-24.
3	Pharma & Vaccines. Product Development Pipeline. April 29 2009.
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8176).