General Information of Drug (ID: DMYHEUA)

Drug Name
ASN007 Drug Info
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Cross-matching ID
PubChem CID
124122366
TTD Drug ID
DMYHEUA

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BVD-523 DMNB4XK Melanoma 2C30 Phase 2 [2]
HH2710 DM0C5MV Solid tumour/cancer 2A00-2F9Z Phase 1/2 [3]
ASTX029 DMVZXIA Solid tumour/cancer 2A00-2F9Z Phase 1/2 [4]
VAN-10-4-eluting stent DM3ZW6A Artery stenosis BD52 Phase 1 [5]
GDC-0994 DMFC2OY Solid tumour/cancer 2A00-2F9Z Phase 1 [6]
JSI-1187 DMVJWBS Solid tumour/cancer 2A00-2F9Z Phase 1 [7]
COR-D DMLXMCB T-cell leukaemia 2A90 Preclinical [8]
6-[(E)-2-(4-Fluoro-phenyl)-vinyl]-9H-purine DMDNG8F Discovery agent N.A. Investigative [9]
⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Extracellular signal-regulated kinase 1 (ERK1) TT1MG9E MK03_HUMAN Inhibitor [1]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 DOI: 10.1158/1538-7445.AM2015-4693
3 Clinical pipeline report, company report or official report of HaiHe Biopharma.
4 Clinical pipeline report, company report or official report of Astex Pharmaceuticals.
5 WO patent application no. 2013,1850,32, Nanotherapeutics for drug targeting.
6 ERK Mutations Confer Resistance to Mitogen-Activated Protein Kinase Pathway Inhibitors
7 National Cancer Institute Drug Dictionary (drug name JSI1187).
8 Corchorusin-D directed apoptosis of K562 cells occurs through activation of mitochondrial and death receptor pathways and suppression of AKT/PKB pathway. Cell Physiol Biochem. 2012;30(4):915-26.
9 Synthesis and biological testing of purine derivatives as potential ATP-competitive kinase inhibitors. J Med Chem. 2005 Feb 10;48(3):710-22.