Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYK1JU)

Drug Name
ASP8232 Drug Info
Indication
Disease Entry ICD 11 Status REF
Diabetic macular edema 9B71.02 Phase 2 [1]
Diabetic nephropathy GB61.Z Phase 1 [2]
Cross-matching ID
TTD Drug ID
DMYK1JU

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Membrane copper amine oxidase (AOC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [3]
Hydralazine DMU8JGH Chronic heart failure BD1Z Approved [4]
BTT-1023 DMIEPJG Psoriasis vulgaris EA90 Phase 2 [5]
BI 1467335 DMTE3UV Diabetic retinopathy 9B71.0 Discontinued in Phase 2 [6]
Vapaliximab DM73EPK Inflammation 1A00-CA43.1 Terminated [7]
Vapill DM30E56 Diabetic complication 5A2Y Investigative [8]
PSX-4206 DMVJDCM Pulmonary disease 1B10-1F85 Investigative [8]
RTU-1096 DMWVBD9 Atopic dermatitis EA80 Investigative [8]
FP-1102 DMGID4T Vascular disease BE2Z Investigative [8]
6-hydroxydopa quinone DM7M58P Discovery agent N.A. Investigative [9]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Membrane copper amine oxidase (AOC3) TT7HC21 AOC3_HUMAN Inhibitor [1]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Clinical pipeline report, company report or official report of Astellas Pharma.
3 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
4 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
5 Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein-1-positive vasculature in inflammation. J Nucl Med. 2013 Aug;54(8):1315-9.
6 Clinical pipeline report, company report or official report of Boehringer Ingelheim.
7 Clinical pipeline report, company report or official report of Huginonline.
8 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).
9 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.