Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYLFQR)

Drug Name

BMS-986120 Drug Info

Synonyms

1478712-37-6; UNII-WDT28B7071; WDT28B7071; 4-(4-(((6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)-5-methylthiazol-2-yl)morpholine; 4-[4-[[6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-1-benzofuran-4-yl]oxymethyl]-5-methyl-1,3-thiazol-2-yl]morpholine; 4-(4-(((6-Methoxy-2-(2-methoxyimidazo(2,1-b)(1,3,4)thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)-5-methylthiazol-2-yl)morpholine; CHEMBL3716726; SCHEMBL15348871; GTPL10269; BDBM176061; EX-A3977; BMS986120; HY-19837; CS-0016978; US9688695, 94; 2-methoxy-6-[6-methoxy-4-[[5-methyl-2-(4-morpholinyl)-4-thiazolyl]methoxy]-2-benzofuranyl]-imidazo[2,1-b]-1,3,4-thiadiazole; Imidazo(2,1-b)-1,3,4-thiadiazole, 2-methoxy-6-(6-methoxy-4-((5-methyl-2-(4-morpholinyl)-4-thiazolyl)methoxy)-2-benzofuranyl)

Indication

Disease Entry	ICD 11	Status	REF
Thrombosis	DB61-GB90	Phase 1	[1]

Cross-matching ID

PubChem CID: 72190270
CAS Number: CAS 1478712-37-6
TTD Drug ID: DMYLFQR

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Prostate apoptosis response-4 (PAWR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BMS-986141	DMTKDIP	Thrombosis	DB61-GB90	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostate apoptosis response-4 (PAWR)	TT3I4WV	PAWR_HUMAN	Antagonist	[2]

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References

1	ClinicalTrials.gov (NCT02439190) CV004-007 Thrombosis Chamber Study. U.S. National Institutes of Health.
2	PAR4 (Protease-Activated Receptor 4) Antagonism With BMS-986120 Inhibits Human Ex Vivo Thrombus Formation. Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):448-456.
3	Protease activated receptor 4 (PAR4) antagonists: Research progress on small molecules in the field of antiplatelet agents. Eur J Med Chem. 2021 Jan 1;209:112893.