Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYNVLZ)

Drug Name
4-iodo-6-phenylpyrimidine Drug Info
Synonyms 41270-96-6; CHEMBL497802; AC-907/25004997; AC1LG8ZQ; SCHEMBL244108; CHEBI:91213; CTK7C3610; MolPort-003-800-888; ZINC331218; BDBM50265608; AKOS005266491; FCH1331127; 4-IPP, &gt
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Cross-matching ID
PubChem CID
817368
ChEBI ID
CHEBI:91213
TTD Drug ID
DMYNVLZ

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting MIF messenger RNA (MIF mRNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ISIS 112690 DM6PO0N Discovery agent N.A. Investigative [3]
Ethyl 7-hydroxy-2-oxo-2H-chromene-3-carboxylate DM7FPX8 Discovery agent N.A. Investigative [4]
ISIS 112724 DMB2O1Y Discovery agent N.A. Investigative [3]
3-benzyl-6-methylbenzo[d]oxazol-2(3H)-one DMGPKIY Discovery agent N.A. Investigative [2]
2-(4-hydroxystyryl)quinolin-8-ol DM8GBH4 Discovery agent N.A. Investigative [4]
7-hydroxy-3-phenyl-2H-chromen-2-one DM2ZE8U Discovery agent N.A. Investigative [4]
6-phenylpyridazin-3-yl thiophene-2-carboxylate DMXTV1B Discovery agent N.A. Investigative [5]
3-benzyl-5-fluorobenzo[d]oxazol-2(3H)-one DMZ85NC Discovery agent N.A. Investigative [2]
ISIS 112696 DMXZS4Y Discovery agent N.A. Investigative [3]
4-((pyridin-4-ylthio)methyl)benzene-1,2-diol DM7X2AY Discovery agent N.A. Investigative [6]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MIF messenger RNA (MIF mRNA) TT6804T MIF_HUMAN Inhibitor [2]

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
2 Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF). Bioorg Med Chem Lett. 2010 Oct 1;20(19):5811-4.
3 US patent application no. 6,268,151, Antisense modulation of macrophage migration inhibitory factor expression.
4 Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening. J Med Chem. 2009 Jan 22;52(2):416-24.
5 An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity. Bioorg Med Chem. 2010 Jul 15;18(14):5425-40.
6 Classification of chemical compounds by protein-compound docking for use in designing a focused library. J Med Chem. 2006 Jan 26;49(2):523-33.