Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYXDB9)

Drug Name

NN-8828 Drug Info

Synonyms

NNC-114-0005; NNC-0114-0000-0005; Anti-IL-21 (inflammation), Novo Nordisk; MIL-21 monoclonal antibody (autoimmune/chronic inflammatory disease), ZymoGenetics; Anti-IL-21 mAb (autoimmune/chronic inflammatory disease), Novo Nordisk; Anti-IL-21 mAb (autoimmune/chronic inflammatory disease), ZymoGenetics; Anti-IL-21 monoclonal antibody (autoimmune/chronic inflammatory disease), ZymoGenetics

Indication

Disease Entry	ICD 11	Status	REF
Autoimmune diabetes	5A10	Phase 1	[1]

Cross-matching ID

TTD Drug ID: DMYXDB9

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Interleukin-21 (IL21)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
IL-21	DM1E4VP	Colorectal cancer	2B91.Z	Phase 2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin-21 (IL21)	TT9QEJ6	IL21_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT01208506) First-in-Man Trial of NNC114-0005 in Healthy Subjects and Subjects With Rheumatoid Arthritis. U.S. National Institutes of Health.
2	Handbook of Therapeutic Antibodies. 2014. 1. Page(995).
3	National Cancer Institute Drug Dictionary (drug id 409696).